Alzheimer’s starts in your 30s, says doc—here are 3 early blood markers that matter

By MDLinx staff

Published May 8, 2025

Key Takeaways

Industry Buzz

"Alzheimer's doesn't start in your 50s and 60s, it starts in your 30s ... staying informed about these markers could help catch early warning signs long before symptoms appear." — Jaban Moore, DC, owner of Redefining Wellness Center

While Alzheimer's disease is often thought of as a condition affecting older adults, Jaban Moore, DC, owner of Redefining Wellness Center says the roots of the disease can be traced back to much earlier stages in life—specifically, the 30s.

For physicians, this is a critical message: Early biomarkers and lifestyle interventions can play a pivotal role in preventing cognitive decline. Here’s how you can help your patients protect their brains long before they hit their 50s or 60s.

These metabolic measurements

It’s no secret that metabolic health plays a key role in neurological function. Dr. Moore stresses that maintaining normal levels of hemoglobin A1C and fasting blood sugar can act as a protective factor against Alzheimer’s.

High blood sugar levels contribute to the formation of advanced glycation end products (AGEs), which can cause neuronal damage.

Encourage your patients in their 30s to monitor these metrics regularly, particularly those with a family history of dementia or other neurological conditions.

This brain health indicator

Albumin is a protein in the blood that helps maintain fluid balance. Elevated levels, however, can indicate dehydration and systemic stress—two factors that can impact brain health.

Dr. Moore highlights that chronic stress raises cortisol levels, which can impair cognitive function. Encouraging hydration and stress management techniques in patients during their 30s could help stave off future brain fog and dementia-related issues.

This vital organ

Your patients' liver health is directly tied to brain health, according to Dr. Moore. Key liver tests such as ALT, AST, alkaline phosphatase, and LDH can help determine whether the liver is under stress.

When the liver is taxed by toxins or inflammation, it can indirectly impact the brain by disrupting metabolic pathways crucial for cognitive function. As doctors, it’s essential to not just treat liver conditions, but also address them early as part of a comprehensive plan for preventing Alzheimer’s and related cognitive issues.

As we continue to understand Alzheimer’s better, it’s becoming clear that early intervention can significantly delay or even prevent the onset of the disease.

By focusing on blood sugar control, hydration, and liver health starting in the 30s, doctors can help their patients set the foundation for long-term brain health. Dr. Moore’s insights serve as a reminder to think proactively about cognitive decline and begin preventive measures well before patients reach their 50s or 60s.