Hospital readmission rate in patients discharged on parenteral antibiotics
As reported in Clinical Infectious Diseases, the hospital readmission rate for patients (n=782) discharged on parenteral antibiotics was 26%. The mean patient age was 58 years. The leading diagnoses were bacteremia, osteomyelitis, and pyelonephritis. The indications for readmission included non-infection related (30%), worsening symptoms (29%), and new infections (19%). The ORs for readmission factors were as follows: each decade increase in age, 1.09; aminoglycoside use, 2.33; resistant organism, 1.57; and number of hospital discharges in prior 12 months, 1.20.
Elevated ?-GT predicts HCC in hepatitis C patients with sustained response
As reported in the Journal of Hepatology, an elevated baseline ɣ-GT level is the strongest predictor of developing HCC in non-cirrhotic patients with hepatitis C and a sustained virologic response (HR = 6.44), followed by age (HR = 3.68).
Rho-associated kinase activity is a biomarker for cardiovascular events
As reported in Hypertension, rho-associated kinase activity is an independent predictor of cardiovascular events. The study involved 633 patients undergoing routine health screening examinations with a median follow-up of 42 months. There were 29 cardiovascular-related deaths, 2 myocardial infarctions, 20 revascularizations, 15 strokes, and 17 hospitalizations for heart failure. The HRs for first cardiovascular event, death, stroke, and revascularization were 2.19, 2.57, 2.14, and 2.68, respectively.