Cerebral Activation and Catastrophizing During Pain Anticipation in Patients With Fibromyalgia

Psychosomatic MedicineBurgmer M et al. | November 18, 2011

The lack of difference in catastrophizing during the experimental pain suggests independent coping mechanisms during experimental and clinical pain. Regarding the importance of the frontal cortex and the periaqueductal gray (PAG) in the descending pain modulation system, it seems reasonable to assume that these functional changes related to the context of stimulus presentation may contribute to central sensitization in fibromyalgia syndrome (FMS).

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