Vascular risk factor control and adherence to secondary preventive medication after ischaemic stroke

By Gynnild MN, Aakerøy R, Spigset O, et al.
Published August 20, 2020

Key Takeaways

Since studies on the adequacy of secondary stroke prevention are insufficient, researchers conducted this multicenter observational study to assess medication adherence, risk factor control, and factors that impact vascular risk profile after ischaemic stroke. In total, 664 home‐dwelling candidates in the Norwegian Cognitive Impairment After Stroke study were assessed 3 and 18 months after having a stroke. The findings reveal suboptimal control of traditional vascular risk factors after ischaemic stroke, with many not meeting guideline‐defined treatment goals for blood pressure, low‐density lipoprotein cholesterol (LDL‐C), and HbA1c. Over 18 months of follow‐up, the authors observed high self‐reported medication adherence and the persistence to secondary preventive drugs decreased only moderately in the same period of time. Although in different directions, age, gender, and the number of medications in use were correlated with vascular risk factor control. However, general practitioner follow-up, psychological distress, and self-reported adherence to medication were not related to achieving recommended targets for treatment, but high self-reported adherence to medication was significantly associated with lower LDL‐C.

Read the full article on Journal of Internal Medicine.

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