Key Takeaways
Via performing this review, researchers sought to critically examine the literature from 2016 to 2021 using positron emission tomography–magnetic resonance imaging (PET/MRI) for the investigation of patients with mild cognitive impairment or dementia. In addition, they discussed the evidence base for widening its application into clinical practice. A comprehensive literature search using the PubMed database led to the retrieval of a total of 116 papers; 39 of these papers were included in the final selection. Per findings, PET/MRI provides additional information concerning the underlying anatomical, metabolic and functional changes linked with dementia when compared with unimodal methods and PET/CT, particularly relating to brain regions including the hippocampus and default mode network. In addition, PET/MRI has improved diagnostic utility, as described by radiologists, which allows improved classification of dementia patients, with important implications for clinical management.
Read the full article on International Journal of Geriatric Psychiatry.