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INTERNAL MEDICINE

Nickel CH, Kellett J, Cooksley T, et al
American Journal of Medicine|August 10, 2020

Researchers sought to determine the diagnoses that are linked with an elevated D-dimer in unselected patients attending emergency departments (ED) as well as investigated their associated outcomes. They conducted a prospective observational study of 1,612 unselected patients attending a Danish ED and identified 765 (47%) of these ED patients with an elevated D-dimer level (ie, ≥ 0.5 mg/L). Patients with elevated D-dimer level were more likely to be admitted to hospital, re-present to health services, and die within 90 days (8.1% of patients). In this unselected ED patient population, they observed elevated D-dimer levels in significant correlation with venous thromboembolism, infection, cancer, heart failure, and anemia.

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