This study was intended to assess, in a real life setting, the rate of strictly normal invasive coronary angiogram (ICA) following a positive noninvasive test result. Researchers enrolled all individuals who had undergone an ICA with a prior positive functional testing (FT) or computed tomography angiogram (CCTA). They divided individuals into 5 subgroups, according to pretest probability (PTP) of having a coronary artery disease (CAD). Main outcomes of ICA were characterized as normal ICA, nonobstructive CAD (non-oCAD), and obstructive CAD (oCAD). A total of 4,952 individuals were included in the study. Compared with FT, CCTA is a better alternative to limit unnecessary ICA regardless of PTP value, without missing abnormal ICA.
Read the full article on American Heart Journal.