Long-term burden of higher body mass index from childhood on adult cardiometabolic biomarkers: A 30-year cohort study

By Liao YY, Chu C, Wang Y, et al
Published September 16, 2020

Key Takeaways

A 30-year cohort study was conducted to evaluate the long-term burden of higher body mass index from childhood on adult cardiometabolic biomarkers. This analysis enrolled a sum of 1,553 individuals aged 6 to 15 years, who were examined 4 or more times for BMI since childhood and followed for 30 years. Researchers estimated the total area under the curve (AUCt) and incremental AUC (AUCi) as the long-term burden and trends of BMI. Researchers obtained cardiometabolic biomarkers including serum uric acid (SUA), fasting blood glucose (FBG), and triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) from venous blood samples. This research distinguishes all patient's BMI growth curves from childhood and highlights that the long-term burden of higher BMI significantly elevates cardiometabolic risk, and the impact of excessive body weight on cardiometabolic originate in early life. For cardiometabolic health, they emphasize the importance of weight control from childhood.

Read the full article on Nutrition, Metabolism & Cardiovascular Diseases.

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