Depression predicts cognitive and functional decline one month after coronary artery bypass graft surgery (NOAHS study)

By Oldham MA, Lin IH, Hawkins KA, et al.
Published October 6, 2020

Key Takeaways

Researchers here examined if baseline depression and cognition are risk factors for decline in the Clinical Dementia Rating Sum‐of‐Boxes (CDR‐SB), which is a combined measure of cognition and function, 1-month post‐CABG surgery. They conducted the Neuropsychiatric Outcomes After Heart Surgery (NOAHS) study, a prospective observational cohort study, including a total of 148 patients undergoing CABG surgery, 124 (83.8%) of whom completed a 1‐month follow‐up assessment. Eighteen (14.5%) individuals had a decline in CDR‐SB. In multivariate regression, older age and depression were noted to be significantly associated with a 1‐month decline. Based on the findings, they suggest considering preoperative depression as a predictor of CDR‐SB decline 1-month post‐CABG.

Read the full article on International Journal of Geriatric Psychiatry.

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