Defining heart disease risk for death in COVID-19 infection

By Li J, Guo T, Dong D, et al
Published August 13, 2020

Key Takeaways

Patients with coronavirus Disease 2019 (COVID-19) frequently report preexisting cardiovascular disease (CVD), researchers here assessed SARS-CoV-2-infected patients with or without CVD for the clinical features and outcomes. Among 596 evaluated patients with COVID-19, CVD was reported in 215 (36.1%). Patients with CVD, vs without CVD, were significantly older and were men in higher proportion. Further, these patients more frequently experienced complications in the course of disease, including acute respiratory distress syndrome, malignant arrhythmias including ventricular tachycardia/ventricular fibrillation, acute coagulopathy, and acute kidney injury. Higher rate of glucocorticoid therapy (36.7% vs 25.5%), Vitamin C (23.3% vs 11.8%), mechanical ventilation (21.9% vs 7.6%), intensive care unit admission (12.6% vs 3.7%) and mortality (16.7% vs 4.7%) were reported for patients with vs without CVD. In the multivariable Cox regression models, following were identified as independent risk factors for death: older age (≥ 65 years old) and patients with CVD.

Read the full article on QJM: An International Journal of Medicine.

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