A nationwide study of the long-term prevalence of dementia and its risk factors in the Swedish intensive care cohort

By Ahlström B, Larsson IM, Strandberg G, et al
Published September 5, 2020

Key Takeaways

This inquiry is performed in a large cohort of intensive care unit (ICU) patients to ascertain if intensive care-treated sepsis represents an independent risk factor for a later diagnosis of dementia. The Swedish Intensive Care Registry was utilized. Participants were adult patients admitted to an ICU in 2005 to 2015 and who survived without a dementia diagnosis 1 year following intensive care admission. Follow-up revealed that dementia diagnosis was received by 6,312 (3%) patients. Findings revealed that patients treated with sepsis in the ICU more commonly developed dementia, but no independent risk for later dementia was conferred by sepsis in the Swedish national critical care cohort. Protective factors were renal replacement therapy and ventilator therapy during the ICU stay.

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