Which radiotherapy approach is best for early breast cancer treatment?

By ecancer, for MDLinx
Published February 11, 2020


Key Takeaways

Treatment with accelerated partial breast irradiation (APBI) using an intensity modulated radiotherapy technique (IMRT) is a viable alternative to whole breast irradiation (WBI) in selected patients with early breast cancer, according to 10-year follow-up data from the APBI IMRT Florence phase 3 trial.

In this randomized, phase 3 trial, Icro Meattini, MD, University of Florence, Florence, Italy, and colleagues compared WBI using three-dimensional conformal radiotherapy with APBI using IMRT. In their 5-year data analysis, Dr. Meattini and colleagues found no significant difference in ipsilateral tumor recurrence or survival rates between the two treatment arms. Findings from their current 10-year analysis validated their previous results, demonstrating that ipsilateral tumor recurrence did not differ significantly between the two arms.

These results were shared at SABCS 2019.


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