Which radiotherapy approach is best for early breast cancer treatment?
Key Takeaways
Treatment with accelerated partial breast irradiation (APBI) using an intensity modulated radiotherapy technique (IMRT) is a viable alternative to whole breast irradiation (WBI) in selected patients with early breast cancer, according to 10-year follow-up data from the APBI IMRT Florence phase 3 trial.
In this randomized, phase 3 trial, Icro Meattini, MD, University of Florence, Florence, Italy, and colleagues compared WBI using three-dimensional conformal radiotherapy with APBI using IMRT. In their 5-year data analysis, Dr. Meattini and colleagues found no significant difference in ipsilateral tumor recurrence or survival rates between the two treatment arms. Findings from their current 10-year analysis validated their previous results, demonstrating that ipsilateral tumor recurrence did not differ significantly between the two arms.
These results were shared at SABCS 2019.
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