Clinical Pearls for Family Medicine

By MDLinx Staff
Published October 6, 2021

Key Takeaways

Check back each month for more Clinical Pearls, and stay sharp with the latest research in Family Medicine with MDLinx.

General Medicine

  • Vitamin D supplementation is associated with a protective effect against colorectal polyps in high latitude locations.

  • Phthalate metabolites are not associated with sex hormone concentrations among all men.

  • Fasting glucagon levels are tied to longitudinal declines in beta-cell function in nondiabetic individuals.

  • Mediterranean dietary interventions improve endothelial function in adults.

  • Poor fitness is associated with risk of insulin resistance.

  • Testosterone therapy leads to small gains in sexual functioning in men with low testosterone levels.

  • Women with Turner syndrome have increased overall mortality and morbidity.

  • Understanding symptom burden of patients with cancer at the end of life is critical.

  • Elevated central venous pressure increases the risk of mortality in the ICU.


  • Hemostatic profile influences susceptibility to migraine.

  • Half of patients with post-RCVS headache recover in about one year.

  • Adolescents with later high school start times have fewer migraines.

  • Osmophobia is significantly related to cranial autonomic symptoms in migraine.

  • Adrenomedullin may be involved in the pathogenesis of migraine.


  • High viral loads are tied to greater cognitive impairment in patients with HCV infection.

  • Antiviral prophylaxis with tenofovir alafenamide fumarate is effective in preventing mother-to-child transmission of hepatitis B virus.

  • HBV may play a role in development of Sjogren’s syndrome.

  • Long-term monotherapy with nucleos(t)ide analogs are a treatment option for chronic hepatitis B.

  • The male reproductive system is a niche for HEV persistence in men with a chronic HEV infection.

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