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Antiapoptotic Seminal Vesicle Protein IV Induces Histamine Release from Human Fc[epsilon]RI+ Cells
International Archives of Allergy and Immunology, 10/26/09
Prevete N et al. – The data are consistent with the antiapoptotic and immunosuppressive properties of SV–IV; confirm a regulatory feature of SV–IV on mammal inflammatory reactivity by either inhibiting the arachidonate cascade pathway or stimulating proinflammatory cytokine release from lymphocyte/monocytes and histamine from FcRI+ cells; raise the possibility of a protective role of SV–IV on implanting hemiallogenic blastocysts against maternal reactive oxygen species and immunological attacks at the uterine implantation site.
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