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Donor Screening for Human T-cell Lymphotrophic Virus 1/2: Changing Paradigms for Changing Testing Capacity
American Journal of Transplantation, 10/22/09
Kaul DR et al. – Donors that are HTLV–1/2 seropositive are infrequently used despite most results being either false positive or resulting from HTLV–2 infection. There is urgent need to encourage the development of assays, instruments and platforms optimized for organ donors that can be used to screen for transmissible disease in donors; these must have appropriate sensitivity and specificity to identify all infections while minimizing organ loss through false positive testing.
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