Urology Medical News about Glucocorticoid Receptor

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The Glucocorticoid Receptor Is Overexpressed in Malignant Adrenocortical Tumors
Journal of Clinical Endocrinology and Metabolism, 10/15/09

Tacon LJ et al. – The immunohistochemical finding of nuclear GR staining identified ACCs with high diagnostic accuracy. The authors propose that GR immunohistochemistry may complement the Weiss score in the diagnosis of ACC in cases that display borderline histology. The possibility that GR is transcriptionally active in these tumors, and may therefore be a therapeutic target, requires further study.

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Selective Prostacyclin Receptor Agonism Augments Glucocorticoid-Induced Gene Expression in Human Bronchial Epithelial Cells
Journal of Immunology, 11/09/09 Relevance Score: 67%

Glucocorticoids Activate Cardiac Mineralocorticoid Receptors During Experimental Myocardial Infarction
Hypertension, 11/09/09 Relevance Score: 66%

BclI polymorphism of the glucocorticoid receptor gene is associated with decreased bone mineral density in patients with endogenous hypercortisolism
Clinical Endocrinology, 10/15/09 Relevance Score: 66%

Glucocorticoid Receptor Interacting Protein-1 Restores glucocorticoid Responsiveness in Steroid-resistant Airway Structural Cells
American Journal of Respiratory Cell and Molecular Biology, 10/06/09 Relevance Score: 66%

Expression of Progesterone Receptor A form and Its Role in the Interaction of Progesterone with Cortisol on Cyclooxygenase-2 Expression in Amnionic Fibroblasts
Journal of Clinical Endocrinology and Metabolism, 10/29/09 Relevance Score: 65%