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See Latest ArticlesMultidrug Resistance in a Urothelial Cancer Cell Line After 1-Hour Mitomycin C Exposure
The Journal of Urology, 10/29/09
Birare N et al. – Results indicate that some multidrug resistance potential exists even in a cloned cell line that is capable of surviving 1 short drug exposure and expanding after that insult. The exposures used are consistent with those probably experienced by many superficial transitional cell carcinoma cells during an intravesical chemotherapy application. The result gives added weight to considering multidrug resistance induction in dose scheduling or drug combinations for topical chemotherapy.
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