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See Latest ArticlesAnti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established target
The Lancet Oncology, 10/01/09
Chen Y et al. – Activation of the androgen receptor is crucial for prostate cancer growth at all points of the illness. Current therapies targeting the androgen receptor, including androgen–depletion approaches and anti–androgens, do not completely inhibit the receptor activity. Notably, promising activity has been shown in early phase trials by MDV3100, a new anti–androgen designed for activity in prostate cancer model systems with overexpressed androgen receptor, and by abiraterone acetate, a CYP17A inhibitor that blocks steroid biosynthesis in the adrenal gland and possibly within the tumour.
Today in Clinical Pharmacology...keeping you current
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Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer
Annals of Oncology, 11/24/09
Effect of Chronic Sildenafil Treatment on Penile Endothelial Function: A Randomized, Double-Blind, Placebo Controlled Study
The Journal of Urology, 11/24/09
Efficacy of Silodosin for Relieving Benign Prostatic Obstruction: Prospective Pressure Flow Study
The Journal of Urology, 11/23/09
Today in Oncology...keeping you current
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High-Resolution Flow Cytometry: a Suitable Tool for Monitoring Aneuploid Prostate Cancer Cells after TMZ and TMZ-BioShuttle Treatment
International Journal of Medical Sciences , 11/25/09
Prospective studies of dietary alpha-linolenic acid intake and prostate cancer risk: a meta-analysis
Cancer Causes and Control, 11/25/09
Dysfunction of natural killer cells in patients with transitional cell carcinoma
Cancer Letters, 11/25/09
Today in Prostate...keeping you current
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High-Resolution Flow Cytometry: a Suitable Tool for Monitoring Aneuploid Prostate Cancer Cells after TMZ and TMZ-BioShuttle Treatment
International Journal of Medical Sciences , 11/25/09
Prospective studies of dietary alpha-linolenic acid intake and prostate cancer risk: a meta-analysis
Cancer Causes and Control, 11/25/09
Salvage high-intensity focused ultrasound for biopsy-confirmed local recurrence of prostate cancer after radical prostatectomy
BJU International, 11/25/09
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