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Effect of Diabetes on Cooling-induced Detrusor Muscle Contraction: Mediation Via Rho-kinase Activation
Urology, 09/30/09
Ismael HN et al. – Cooling–induced contractions in control and diabetic detrusor muscle preparations are highly calcium dependant. It also involves activation of Rho–kinase, which might be upregulated in the diabetic detrusor muscle. These results may help in the management of diabetes–induced incontinence due to involuntary detrusor muscle activity.
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