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See Latest ArticlesPhase II trial of short-term neoadjuvant docetaxel and complete androgen blockade in high-risk prostate cancer
British Journal of Cancer, 09/17/09
Mellado B et al. – The low probability of curing high–risk prostate cancer (PC) with local therapy suggests the need to study modality of therapeutic approaches. To this end, a prospective phase II trial of neoadjuvant docetaxel (D) and complete androgen blockade (CAB) was carried out in high–risk PC patients. Short–term neoadjuvant D and CAB induced a 6% pCR rate, which is close to what would be expected with ADT alone. The combination was generally well tolerated.
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