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See Latest ArticlesDKC1 overexpression associated with prostate cancer progression
British Journal of Cancer, 09/17/09
Sieron P et al. – DKC1 upregulation in prostate cancers is common and likely to be necessary for extensive tumour growth. The phenotype of prostate carcinoma cell lines after dyskerin downregulation suggests that its most critical function is sustaining protein biosynthesis. Intriguingly, compromised function and overexpression of dyskerin can both contribute to cancer development.
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