Urology Medical News about Prostate cancer

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. 2008 Exclusive Survey—Earnings: Good news for primary care income

3. Medicare pay-for-reporting effort draws fire from frustrated doctors

4. Debunking Myths in the US Healthcare System

5. Doctors and the DEA Free full text

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Prostate cancer: a newly discovered route for testosterone to reach the prostate
Andrologia, 09/11/09

Gat Y et al. – The authors suggest a time–window for eradication of localised, androgen–sensitive, PCa cells. They anticipate that this treatment may retard, stop or even reverse the development of the disease. A mechanism for the evolution of PCa is discussed.

Exclusive Author Commentary
Yigal Gat, 10/02/09

To the Editor MdLinx For the first time it has been proven that varicocele is a bilateral disease, the primary cause for male infertility and low testosterone level, it is now discovered as well as the true cause for enlargement of the prostate and for the development of prostatic cancer For the first time it is proven that super-selective venography and sclerotherapy (Gat Goren Technique), which in the past helped to treat male infertility also cures early localized prostate cancer and helps to decrease prostate volume. This pathology develops when the testicular venous drainage system ceases to function due to the destruction of the one way valves in the internal spermatic veins (bilateral varicocele). This treatment includes occlusion by sclerosis of right and left spermatic veins with incompetent one way valves including the entire network of vertically oriented associated bypasses that each one of these exerts elevated hydrostatic pressure in the testicular venous drainage system, which found to be the cause that divert the flow of free testosterone with concentration some 130 folds the normal from the testes - the testosterone production site, directly to the prostate. These chain of pathologic processes was found to develop BPH and prostate cancer. Using a variation of our technique for bilateral varicocele sclerotherapy (Gat-Goren technique), we have shown, in our series of patients, that limited prostate cancer can be eliminated and prostatic enlargement be reversed. Our treatment cuts off the flooding of the prostate gland by high concentrations of free testosterone which occurs in patients with bilateral varicocele. We would like to stress two of our conclusions via molecular biology analysis of mutant-cancrous cells: (1) There is a limited window of opportunity to treat early prostate cancer effectively by this method. (2) Treating prostate cancer by ADT (androgen deprivation therapy) without stopping the testosterone influx directly from the testes through the pelvic venous interconnections risks the production of aggressive, androgen independent cell lines, and, ultimately, treatment failure. Yigal Gat Michael Goren (Gornish)

<< Previous
Clinical Implications of Proteinuria in Renal Transplant...

Next >>
Assessing the Impact of Ischaemia Time During Partial Nephrectomy