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Chen SC et al. – The authors report the case of a 49–year–old female, under chronic hemodialysis therapy who received a living transplant from her husband. Both of them had the same blood type and the result of the mixed lymphocyte culture test was acceptable before transplantation. Accelerated acute rejection (AAR) after kidney transplantation may occur because of the pre–sensitization of the host cell against the graft antigens. Protocol repeated biopsies may be required in those patients who do not recover after an initial rejection to detect early second pathologies.

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