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De Novo Kidney Transplant Recipients Need Higher Doses of Advagraf Compared With Prograf to Get Therapeutic Levels
Transplantation Proceedings, 09/10/09
Crespo M et al. – Among de novo renal cases, the new once–daily formulation of tacrolimus offered a similar short–term efficacy profile as the twice–daily tacrolimus. But it was necessary to use up to a 50% higher dose of Advagraf than Prograf to achieve similar trough levels during the first 6 months.
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