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New insights into small-molecule inhibitors of Bcr-Abl
Medicinal Research Reviews, 08/31/09
Schenone S et al. – The authors will report the most interesting second–generation Abl and dual Src/Abl inhibitors recently entered in clinical trial, but also the new ATP–competitive and uncompetitive inhibitors published in the last few years, focusing on their chemical structure, mechanism of action, and structure–activity relationship.
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