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Ductal adenocarcinoma of the prostate diagnosed on transurethral biopsy or resection is not always indicative of aggressive disease: implications for clinical management
BJU International, 08/26/09
Aydin H et al. – Most DCP diagnosed on UB or TURP in this contemporary series was associated with aggressive PA, but a subset presented as a small periurethral tumour with no concomitant acinar PA, and was eradicated by the initial biopsy/TURP alone. The authors recommend that patients with a diagnosis of DCP on UB or TURP undergo follow–up TURP and TRUSB before radical surgery is offered.
Ming Zhou, 08/26/09
| This study was prompted by my personal experience with one patient whose radical prostatectomy showed no residual cancer after an initial diagnosis of prostate ductal carcinoma on transurethral biopsy. To be clear, most of the patients with a diagnosis of prostate ductal carcinoma on transurethral biopsy have aggressive, high stage cancer. Some patients, just like my patient, however, may have an early disease localized to the verumontanum area and patients may not need a radical surgery. So before offering radical prostatectomy to patients, it is prudent to do a repeat TURP and/or transrectal prostate biopsy. |
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