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See Latest ArticlesAntimuscarinics and overactive bladder: other mechanism of action
Neurourology and Urodynamics, 08/27/09
Yamaguchi O – Acetylcholine released during the storage phase could be expected to enhance the myogenic contractile activity of the detrusor, which can generate afferent signals. It is suggested that antimuscarinics may decrease bladder afferent activity by blocking MR in the above sites, thereby improving OAB symptoms.
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