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See Latest ArticlesThe effects of intracrystalline and surface-bound proteins on the attachment of calcium oxalate monohydrate crystals to renal cells in undiluted human urine
BJU International, 08/20/09
Grover PK et al. – Inorganic COM crystals bind significantly more strongly to MDCK–II cells than urinary crystals precipitated from sieved, centrifuged and filtered, and ultrafiltered urine, and binding affinity is inversely related to the concentration of protein in the urine in which they are formed. While both intracrystalline and superficial CME proteins reduce the attachment of COM crystals to MDCK–II cells, those located on the crystal surface have a greater influence than those incarcerated within the mineral bulk.
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