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Effects of the 5 alpha-reductase inhibitor dutasteride on gene expression in prostate cancer xenografts
The Prostate, 08/18/09
Schmidt LJ et al. – The authors have identified multiple pathways outside of the androgenic pathway in prostate cancer xenografts affected by treatment with dutasteride. These findings provide insights into the function of dutasteride within the tumor microenvironment, potentially allowing for development of agents that can be used in combination with this drug to further enhance its effectiveness.
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