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Assessing the Effects of Transforming Growth Factor-beta1 on Bladder Smooth Muscle Cell Phenotype. II. Modulation of Collagen Organization
The Journal of Urology, 08/24/09
Parekh A et al. – Changes in collagen architecture organization in response to transforming growth factor–beta1 indicate changes in the bladder smooth muscle cell phenotype, resulting in altered cell/extracellular matrix interactions. Changes in this relationship at the microscopic level could be an important component of tissue remodeling and subsequent dysfunction, and indicate a possible role for transforming growth factor–beta1 in bladder pathology cases.
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