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Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists
Proceedings of the National Academy of Sciences of the United States of America, 07/24/09
Joseph JD et al. – Although the therapeutic potential of these antiandrogens is apparent, it is the demonstration that it is possible, to modulate the interaction of cofactors with agonist–activated AR, using second–site modulators, that has the greatest potential with respect to the therapeutic exploitation of AR and other NRs.
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