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The effects of hepatocyte growth factor and insulin-like growth factor-1 on the myogenic differentiation of satellite cells in human urethral rhabdosphincter
Neurourology and Urodynamics, 07/20/09
Sumino Y et al. – HGF did not induce myogenic differentiation of RS satellite cells. Conversely, IGF–1 promoted myogenic differentiation of RS satellite cells via the PI3–K pathway likewise proliferating RS satellite cells. These findings may be useful for developing novel techniques for regenerating the human RS to treat urinary incontinence.
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