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Urinary excretion of ganciclovir contributes to improvement of adenovirus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation
Pediatric Transplantation, 07/20/09
Nakazawa Y et al. – A nine–yr–old girl developed AdV–associated HC after bone marrow transplantation. Intravenous GCV markedly reduced urinary AdV DNA loads and improved clinical findings. This appeared to result partly from a high concentration of GCV in urine. GCV may be effective for AdV–induced HC without definitive disseminated infection.
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