Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Doctors and the DEA Free full text
Your Article Summary
See Latest ArticlesThe role of caveolin-1 in prostate cancer: clinical implications
Prostate Cancer & Prostatic Diseases, 07/08/09
Thompson TC et al. - In a review of the role of caveolin-1 (cav-1) in prostate cancer (PCa), it appears that secreted cav-1 is a potential biomarker and therapeutic target for PCa.
Methods- Cav-1 is reportedly overexpressed in PCa cells and is associated with disease progression.
- Specific oncogenic activities of cav-1 associated with Akt activation also occur in PCa.
- A membrane-associated protein, cav-1, is secreted by PCa cells; results of recent studies showed that secreted cav-1 can stimulate cell survival and angiogenic activities, defining a role for cav-1 in the PCa microenvironment.
- Serum cav-1 levels were higher in PCa pts than in control men without PCa, and the preoperative serum cav-1 concentration had prognostic potential in men undergoing radical prostatectomy.
Related Articles
Lipid Rafts and Caveolin-1 Are Required for Invadopodia Formation and Extracellular Matrix Degradation by Human Breast Cancer Cells
Cancer Research, 11/17/09
Relevance Score: 80%
Caveolin-1 Promotes Autoregulatory, Akt-Mediated Induction of Cancer-Promoting Growth Factors in Prostate Cancer Cells
Molecular Cancer Research, 11/16/09
Relevance Score: 80%
High ACAT1 expression in estrogen receptor negative basal-like breast cancer cells is associated with LDL-induced proliferation
Breast Cancer Research and Treatment, 11/04/09
Relevance Score: 77%
Activity of the multikinase inhibitor dasatinib against ovarian cancer cells
British Journal of Cancer, 11/02/09
Relevance Score: 77%
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Mutation analysis of the MSMB gene in familial prostate cancer
British Journal of Cancer, 12/10/09
Small Variations in Crucial Steps of Tunel Assay Coupled to Flow Cytometry Greatly Affect Measures of Sperm DNA Fragmentation
Journal of Andrology, 12/09/09
Estrogen Receptor alpha and beta Polymorphisms Are Associated with Semen Quality
Journal of Andrology, 12/08/09
Today in Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
Mutation analysis of the MSMB gene in familial prostate cancer
British Journal of Cancer, 12/10/09
[F18]-fluoroethylcholine combined in-line PET-CT scan for detection of lymph-node metastasis in high risk prostate cancer patients prior to radical prostatectomy: Preliminary results from a prospective histology-based study
European Journal of Cancer, 12/10/09
Comorbidity, body mass index, and age and the risk of nonprostate-cancer-specific mortality after a postradiation prostate-specific antigen recurrence
Cancer, 12/10/09
Today in Prostate...keeping you current
Receive free subspecialty "5-minute updates" via email
Mutation analysis of the MSMB gene in familial prostate cancer
British Journal of Cancer, 12/10/09
[F18]-fluoroethylcholine combined in-line PET-CT scan for detection of lymph-node metastasis in high risk prostate cancer patients prior to radical prostatectomy: Preliminary results from a prospective histology-based study
European Journal of Cancer, 12/10/09
Comorbidity, body mass index, and age and the risk of nonprostate-cancer-specific mortality after a postradiation prostate-specific antigen recurrence
Cancer, 12/10/09
Article Search
Sponsor