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See Latest ArticlesBeyond PSA: Utility of novel tumor markers in the setting of elevated PSA
Urologic Oncology: Seminars and Original Investigations, 07/01/09
Lin DW - In a review of the utility of novel tumor markers in the setting of elevated prostate-specific antigen (PSA), this article will first highlight several characteristics of an ideal biomarker, then focus on select emerging biomarkers for detection of prostate cancer (PCa).
Methods- Introduction of prostate-specific antigen (PSA) for PCa screening and detection has been used for over 20 yrs and has dramatically changed the face of PCa.
- Although it is a highly sensitive serum test, its routine use has been the subject of continued controversy owing to its limited specificity.
- Due to this lack of specificity, many have proposed modifications of PSA in an attempt to bolster the performance of this analyte.
- The human genome project and high throughput gene expression profiling has recently yielded several promising molecular biomarkers for PCa detection beyond PSA or PSA modifications.
Today in Oncology...keeping you current
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Risk of dying from prostate cancer in men randomized to screening
Cancer, 10/13/09
Zinc and prostatic cancer
Current Opinion in Clinical Nutrition & Metabolic Care, 10/14/09
Early PSA decrease is an independent predictive factor of clinical failure and specific survival in patients with localized prostate cancer treated by radiotherapy with or without androgen deprivation therapy
Annals of Oncology, 10/16/09
Today in Prostate...keeping you current
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Risk of dying from prostate cancer in men randomized to screening
Cancer, 10/13/09
Zinc and prostatic cancer
Current Opinion in Clinical Nutrition & Metabolic Care, 10/14/09
Early PSA decrease is an independent predictive factor of clinical failure and specific survival in patients with localized prostate cancer treated by radiotherapy with or without androgen deprivation therapy
Annals of Oncology, 10/16/09
Today in Radiology/Diagnostics...keeping you current
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Bacterial Sepsis After Prostate Biopsy—A New Perspective
Urology, 10/21/09
Evaluating the combined effect of comorbidity and prostate-specific antigen kinetics on the risk of death in men after prostate-specific antigen recurrence
Journal of Clinical Oncology, 11/02/09
Sonographic detection of renal and ureteral stones. Value of the twinkling sign
International Braz J Urol, 10/30/09
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