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Significance of HLA Nondependent Risk Factors of Chronic Transplant Nephropathy for the Development of Endothelial Dysfunction After Kidney Transplantation
Transplantation Proceedings, 06/26/09
Horcicka V et al. - More than 40% of renal allografts show chronic transplant nephropathy (CTN) early after renal transplantation. Cardiovascular disease is the leading cause of death in this population. Thus endothelial dysfunction represents an early angiopathy causing CTN and atherosclerosis. The time on hemodialysis, the presence of hyperlipoproteinemia, and the recipient age significantly contribute to endothelial dysfunction during the first year after transplantation.
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