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See Latest ArticlesCombination of alfuzosin and tadalafil exerts an additive relaxant effect on human detrusor and prostatic tissues in vitro
International Braz J Urol, 06/23/09
Oger S et al. - The combination of alfuzosin and tadalafil exerts an additive effect of inhibiting adrenergic smooth muscle tone of prostatic tissue and EFS-induced detrusor contractions and conversely, of enhancing adrenergic relaxation of detrusor precontracted with carbachol. These experiments provide experimental support for the clinical investigation of the combination of alpha1-blockers and PDE5 inhibitors in the treatment of LUTS.
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