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The Role of Chemotherapy in Upper Tract Urothelial Carcinoma
Advances in Urology, 06/18/09

O'Donnell PH et al. - Data does not exist with adjuvant therapy in bladder cancer, and adjuvant therapy for upper tract disease is further complicated by the difficulty of administering cisplatin-based regimens to patients who may suffer a decrement in renal function following nephrectomy. Therefore, until and unless specific trials are conducted, the most reasonable standard for locally advanced upper tract urothelial cancer is neoadjuvant, cisplatin-based combination chemotherapy prior to nephrectomy and surgical resection.

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Proton radiation for localized prostate cancer

A phase 2 clinical trial of nab-paclitaxel in previously treated and chemotherapy-naive patients with metastatic melanoma
Cancer, 11/09/09 Relevance Score: 92%

Selective internal radiation therapy for liver metastases from colorectal cancer
Cochrane Reviews, 10/09/09 Relevance Score: 91%

Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial
The Lancet Oncology - Online First, 10/30/09 Relevance Score: 90%

Phase 2 trial results with the novel neurokinin-1 receptor antagonist casopitant in combination with ondansetron and dexamethasone for the prevention of chemotherapy-induced nausea and vomiting in cancer patients receiving moderately emetogenic chemotherapy
Cancer, 10/20/09 Relevance Score: 90%

Ranked importance of outcomes of first-line versus repeated chemotherapy among ovarian cancer patients
Supportive Care in Cancer, 10/01/09 Relevance Score: 90%