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Differential kinetics of effector and regulatory T cells in patients on calcineurin inhibitor–based drug regimens
Kidney International, 06/05/09
Presser D et al. - The studies suggest that there is an initial decrease of Tregs and effector T cells as a consequence of a direct inhibitory effect of immunosuppressive drugs. In the long term, persistently low Treg levels may favor normalization of effector T cells to ensure sufficient pathogen control.
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