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Galvao DA et al. - In this brief review authors discuss the incidence of cardiovascular and metabolic complications during/following ADT from large cohort studies, the increased risk factors for cardiovascular and metabolic disease from cross-sectional and prospective studies and the use of physical exercise as a countermeasure in this new era of ADT-related toxicity. It is clear that exercise has the potential to provide a myriad of benefits to men undergoing ADT that may result in reduced morbidity and mortality, and subsequently improve quality of life.

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