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First-year costs of treating prostate cancer: estimates from SEER-Medicare data
Prostate Cancer & Prostatic Diseases, 05/27/09

Roehrborn CG et al. - The data show that health-care costs were significant and varied by stage. With average first-year PCa-related costs of US$13 091, prevention strategies have the potential to reduce health-care costs.

Exclusive Author Commentary
M Stokes, 05/28/09

We used the SEER-Medicare linked database to estimate mean per-patient costs related to prostate cancer (PCa) during the first year following diagnosis. Cost estimates and treatment patterns are presented by initial cancer stage. We found that almost one-third of all PCa patients did not receive an active therapy. These patients were slightly older (mean age: 76 years) vs. those receiving active treatment (mean age: 73.2 years). Receipt of external beam radiation and brachytherapy was more common among early vs higher staged patients. Very few patients received cryotherapy (0.1%) or bilateral orchidectomy (0.2%). We also found that PCa-related costs increased according to cancer stage (Stage I: $11,590; Stage II: $12,191; Stage III: $13,920; and Stage IV: $18,371 All: $13,091). Our analyses shed light on the magnitude of first-year PCa-related costs and may be useful in estimating the potential economic benefits of prevention strategies. Future research should focus on estimating costs during later phases of care (i.e., continuing and terminal care) and producing life-time estimates.

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Risk of dying from prostate cancer in men randomized to screening
Cancer, 10/13/09 Relevance Score: 72%

Validation in a Multiple Urology Practice Cohort of the Prostate Cancer Prevention Trial Calculator for Predicting Prostate Cancer Detection
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A prospective study of lifetime physical activity and prostate cancer incidence and mortality
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Association of 17 prostate cancer susceptibility loci with prostate cancer risk in Chinese men
The Prostate, 11/02/09 Relevance Score: 71%

Prostate specific antigen for early detection of prostate cancer: longitudinal study
British Medical Journal, 10/08/09 Relevance Score: 71%