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See Latest ArticlesAdenosine receptor expression in Escherichia coli-infected and cytokine-stimulated human urinary tract epithelial cells
BJU International, 05/21/09
Save S et al. - The data showed a subtype-selective plasticity among adenosine receptors in urinary tract epithelial cells in response to UPEC-infection and cytokines. There was a consistent up-regulation of A2A receptors in kidney and bladder epithelial cells. Functionally, A2A receptor activation reduced UPEC-induced IL-6 secretion. These findings suggest that adenosine might be a previously unrecognized regulator of the mucosal response in urinary tract infection.
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