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Chen Y et al. - The authors hypothesize that blockade of [alpha]1A-adrenoceptor may suppress the motility of these organs, thereby inhibiting sperm transport and achieving contraception, and the [alpha]1A-selective antagonists can act as a male contraceptive. If the hypotheses can be further supported with clinical trials it will shift the paradigm for male-based contraception and provide a wider range of choice for all.

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