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MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells
Biochemical and Biophysical Research Communications, 05/13/09
Li T et al. - Data suggested that miR-21 could promote apoptosis resistance, motility, and invasion in prostate cancer cells and these effects of miR-21 may be partly due to its regulation of PDCD4, TPM1, and MARCKS. Gene therapy using miR-21 inhibition strategy may therefore be useful as a prostate cancer therapy.
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