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Testicular stem cells for fertility preservation: Preclinical studies on male germ cell transplantation and testicular grafting
Pediatric Blood & Cancer, 05/08/09
Schlatt S et al. - Despite the current limitations in regard to the generation of sperm from cryopreserved male germline cells and tissues, protocols for cryopreservation of testicular tissue are available and reveal a promising outcome. Since future improvements of germ cell transplantation and grafting approaches can be assumed, bioptic retrieval and cryopreservation of testicular tissue fragments should be performed in oncological patients at high risk of fertility loss since this is their only option to maintain their fertility potential.
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