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The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on protein kinase A catalytic subunits
Journal of Clinical Endocrinology and Metabolism, 05/01/09
Louiset E et al. - The results indicate that, in human PPNAD tissues, dexamethasone paradoxically stimulates cortisol release through a GR-mediated effect on PKA catalytic subunits.
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