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Farley SJ - Infants fed milk products contaminated with high concentrations of the industrial chemical melamine are seven times more likely to develop urinary stones than unexposed children. Preterm birth exacerbates this risk. The lack of stone-specific symptoms such as oliguria, edema, distress during urination and passing of calculi among affected children indicates that investigation for urolithiasis should be based on history of melamine exposure rather than on symptomatology. Ultrasound examination of exposed infants should be performed, with operators being cognizant of the fact that melamine-associated stones often do not show the shadowing that is typical of urinary calculi.

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