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Does one have a sexual life 15 years after external beam radiotherapy for prostate cancer? Prospective patient-reported outcome of sexual function comparison with age-matched controls
Urologic Oncology: Seminars and Original Investigations, 03/13/09

Fransson P et al. - In a study to examine the sexual function in pts 15 yrs after external beam radiotherapy (EBRT) for localized prostate cancer (LPC), it was found that sexual activity 15 yrs after EBRT for LPC was very low, as was the probability of achieving an erection. Pts with a progressive disease and treated with hormones reported worse sexual and erectile function. LPC-free men showed higher sexual activity, lower sexual bother, and better erectile function than pts.

• The cohort consisted of 29 men surviving from a group of 181 men treated between 1986 and 1989.
• Of the originally reported 141 controls, 62 were eligible and 34 completed the questionnaires.
• Sexual function was assessed using 2 questionnaires, Prostate Cancer Symptom Scale (PCSS) and International Index of Erectile Function (IIEF-5).

• 23 pts (78%) and 13 controls (38%) were not sexually active.
• None of the pts and 14 controls had enough of an erection to perform intercourse.
• 17 pts (94%) and 14 controls (64%) had severe erectile dysfunction.
• Pts with clinical progression and who had received hormone treatment had decreased sexual desire.
• No significant differences were measured between pts without progression/hormone treatment and the controls.

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