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Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in irritable bowel syndrome
Neurogastroenterology and Motility, 02/04/09
Chang L et al. - Although dysregulations in stress-responsive systems such as the HPA axis and mucosal immune function are demonstrated in IBS, they do not appear to have a primary role in modulating IBS severity and abdominal pain.
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