The genetics of male fertility--from basic science to clinical evaluation
Journal of Andrology, 08/10/2012
Pastuszak AW et al. – The authors' understanding of male fertility has increased dramatically over the past several decades, in large part due to advances in technology and the ability to rapidly analyze large quantities of high–resolution genetic data. These research efforts have led to an understanding of some of the genes involved in male fertility and have enabled us to test for defects in these genes that result in infertility in men. However, the authors' understanding of male fertility remains far from comprehensive, and many genes involved in male fertility likely remain to be identified and their mechanisms of action elucidated. This can only be accomplished through continued, persistent investigations using cutting–edge technologies.